$3.8 trillion. Every year.

Chronic illness drives 530,000 Americans into medical bankruptcy annually. The pharmaceutical industry's practices may be actively worsening the crisis.

$220B

Americans' medical debt

66.5%

Bankruptcies caused by medical expenses

771,480

Homeless population connected to medical crisis

Chronic illness represents nearly 20% of GDP. Despite these staggering losses, the system profits from perpetual treatment over cures - evidenced by $2.9 billion in fraud settlements in 2024 alone.

The Cascade

From illness to homelessness.

Step 1: Job Loss

58% of US employees have chronic conditions. Multiple conditions reduce employment probability by 11-29%. Workers miss 3-9 additional days annually.

Step 2: Financial Collapse

20 million people carry medical debt. More than half incurred it while insured. Medical expenses are the leading cause of bankruptcy.

Step 3: Housing Loss

Medical debt extends homelessness by more than 2 years. 85% of homeless have chronic conditions - median of 4 conditions versus 2 in general population.

Real case: Kayce Atencio suffered a heart attack at 19, declared bankruptcy by 25, and spent years without stable housing. A diabetic in Savannah lost her toe, then her job, then her leg, accumulating hundreds of thousands in debt before becoming homeless.

Where the $3.8 trillion goes.

Direct healthcare spending$1.1-4.9 trillion

Chronic diseases drive 90% of total healthcare expenditures

Lost productivity$530B - $1.1T

Absenteeism, presenteeism, early retirement

Unpaid family caregiving$600-873.5B

48 million caregivers provide 36 billion hours of unpaid care

Disability payments$213B

SSDI and SSI supporting 7.3 million disabled workers and families

This equals $11,000-24,000 per American annually - more than the entire federal budget.

The Industry

Pharma profits from chronic treatment.

17.1%

Adults taking 5+ medications (up from 8.2% in 1999)

88%

Increased hospitalization risk from polypharmacy

$2.9B

False Claims Act settlements in 2024

1,200%

Insulin price increase ($21 to $274)

Prescribing Cascades

Initial drugs cause side effects requiring additional medications, generating new chronic conditions. 46 documented cascades identified - like amlodipine causing edema leading to diuretic prescriptions in 1 in 22 patients.

Over 25% of top prescribers for opioid maker Mallinckrodt were later convicted, disciplined, or fined for wrongdoing.

The system profits from sickness.

Fee-for-Service Model

Rewards volume over outcomes. A sick patient is worth more than a healthy patient. 90% of $4.9 trillion goes to chronic and mental health conditions.

Prevention Defunded

CDC's $1.4 billion Center for Chronic Disease Prevention completely eliminated in 2025. Budget only increased 6% over two decades (inflation-adjusted).

Fragmented Care

47% of Americans with chronic illness receive "noncontinuous, low-quality, duplicated care" from providers operating in silos.

Racial disparity: 27.9% of Black households carry medical debt vs 17.2% of white households. People of color with medical debt experience homelessness one year longer than white individuals.

A self-reinforcing cycle.

Chronic illness generates massive costs while the systems designed to address it actively perpetuate the problem. Costs could double within 30 years.

Breaking this requires transitioning from fee-for-service to prevention-focused models, rebuilding public health infrastructure, and aligning pharmaceutical incentives with patient outcomes.